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Dementia metrics showed a continuous increase in prevalence, incidence, mortality, and disability adjusted life years (DALYs) rates worldwide during the last three decades, and will more than double in mortality burden over the next 20 years. Background: The burden associated with Alzheimer’s disease is recognized as one of the most pressing issues in …ORIGINAL ARTICLE Open Access Did tuition fees in Germany constrain students’ budgets? New evidence from a natural experiment Stephan Thomsen1,2,3,4* and Friederike von …For creating PDF files. You can use the following multiple methods: 1. Open Acrobat and choose the Tool Option, then “Create PDF”. 2. Use Microsoft Word or Google Doc to Create any Document and save that file as a PDF.Use the file selection box at the top of the page to select the PDF files from which you want to remove protection. Enter the password that was used to encrypt the PDF. Remove the protection from the PDFs by pressing the corresponding button. 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